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Clinical Problem Solving: Radiology
January 2005

Radiology Quiz Case 4—Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2005;131(1):79-80. doi:10.1001/archotol.131.1.79

Ameloblastoma is an uncommon neoplasm. It accounts for approximately 20% of all odontogenic tumors and represents only 1% of all tumors in the jaws. The mandible is the site of origin in 80% of cases.1 Males and females are affected equally, usually in the third or fourth decade of life.2 The tumor is thought to arise from residual epithelium of the tooth-forming apparatus, such as the epithelial cell rests of Malassez; epithelium of odontogenic cysts; basal cells of the surface epithelium; epithelium of the enamel organ; and heterotopic epithelium of extraoral sites, such as the pituitary gland.3

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