Foregut duplication cysts are heterotopic rests of foregut-derived epithelium that are usually found in the abdomen and thorax but occur rarely in the head and neck. We describe the first case (to our knowledge) of a hypopharyngeal foregut duplication cyst containing both gastric and pancreatic tissue. The case involved a neonate who was born with stridor and cyanosis and who required immediate intubation because of airway obstruction due to a large hypopharyngeal mass. Magnetic resonance imaging and computed tomography were helpful in localizing the lesion. Direct laryngoscopy revealed a 4.5 × 2.5-cm mass in the hypopharynx, originating 2 mm above the esophageal inlet. The mass was excised, which is the treatment of choice. We also review the literature and discuss the pathogenesis of foregut duplication cysts.
Edwards J, Pearson S, Zalzal G. Foregut Duplication Cyst of the Hypopharynx. Arch Otolaryngol Head Neck Surg. 2005;131(12):1112-1115. doi:10.1001/archotol.131.12.1112