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October 1917

THE PROPHYLACTIC USE OF PERTUSSIS VACCINE CONTROLLED BY THE COMPLEMENT FIXATION TEST

Author Affiliations

MINNEAPOLIS
From the Department of Pediatrics and the Department of Pathology and Bacteriology, University of Minnesota.

Am J Dis Child. 1917;14(4):283-286. doi:10.1001/archpedi.1917.01910100052004
Abstract

During the past five years numerous clinical reports have been made on the prophylactic and curative value of pertussis vaccine. Graham,1 Ladd2 and Bamberger3 reported favorably on its curative power in small doses. Hess4 was fortunate in being able to observe the effect of vaccines during an epidemic of whooping cough in an institution; he was skeptical of its curative power, but was favorably impressed by its prophylactic value, even though 10 per cent, of his treated patients developed pertussis. Hartshorn and Moeller,5 after reviewing the literature and reporting cases of their own, thought the vaccine worthy of further trial, but did not recommend its general use. Abt6 says that "the possibility of immunizing by vaccination is still an open question for pertussis." Luttinger,7 after an extensive experience with the whooping-cough clinic of the New York City Health Department, concludes that pertussis vaccine

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