The subject of infantilism has come in recent years into ever increasing prominence. The term should be applied not only to adolescents or adults who possess in some degree the bodily and often the psychic characteristics of infancy, but to children of any age in whom there is a persistence of characters, especially sexual, which belong to a period of life decidedly earlier than the actual age of the patient. Further, a sharp distinction should be drawn between infantilism and nanism. There may be dwarfs who are in no respects infantile, such as those of a rachitic or achondroplastic nature. As Hastings Gilford1 has pointed out, there has been in them an arrest of growth, but not of development. Less often there may be cases of infantilism which are the reverse of being dwarfs, as in one of the instances which I desire to record.
Much confusion still exists,
GRIFFITH JPC. INFANTILISM, WITH TWO CASES OF THE BRISSAUD AND THE FRÖLICH TYPES, RESPECTIVELY. Am J Dis Child. 1918;16(2):103–108. doi:10.1001/archpedi.1918.01910140042004