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March 1920


Am J Dis Child. 1920;19(3):181-188. doi:10.1001/archpedi.1920.01910210015002

This condition was first described by Vorlik in 1849. Up to 1906. 140 cases had been reported. So many names have been used in the description of bone abnormalities in infants that an uncertainty remains as to just what is meant in some of these descriptions. For example, Lovett and Nichols,1 after a careful study of all the case reports, conclude that only fourteen of these are true cases of osteogenesis imperfecta congenita. Since the introduction of the roentgen ray the descriptions have been more accurate. Valuable articles on the subject have also recently been contributed by Schwartz and Bass,2 Griffith,3 Hess,4 Bookman5 and Mixsell.6

Two types are recognized, namely: osteogenesis imperfecta congenita and osteogenesis imperfecta tarda. Authors are convinced that there is a clearly defined distinction between these two types. It is a rare systemic disease of unknown etiology, characterized by imperfect development

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