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August 1921

A CONTRIBUTION TO THE TOPOGRAPHIC ANATOMY OF THE THYMUS GLAND, WITH PARTICULAR REFERENCE TO ITS CHANGES AT BIRTH AND IN THE PERIOD OF THE NEW-BORN

Author Affiliations

MINNEAPOLIS

Am J Dis Child. 1921;22(2):120-144. doi:10.1001/archpedi.1921.04120020017002
Abstract

The peculiar life history of the thymus gland in man is reflected in its topography, which is modified from time to time by different phases of its growth and involution and by changes in the neighboring structures and viscera. These changes in thymus topography begin during fetal life and are particularly striking at birth when the chest and its contained organs are greatly modified as respiration is established. The natal changes of the thymus have received comparatively little study, and the lack of information on this subject seems to have led to considerable confusion regarding the normal form and extent of the organ in early postnatal life. The following account is an attempt to trace in detail these early modifications in thymus topography with particular reference to the normal or usual conformation and relations of the structure in early infancy. This work was done in the Department of Anatomy of

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