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October 1921

ON THE ETIOLOGY OF HEMORRHAGIC DISEASE OF THE NEW-BORN

Author Affiliations

SAN FRANCISCO
From the Department of Pediatrics of the University of California and the University of California Hospital.

Am J Dis Child. 1921;22(4):351-357. doi:10.1001/archpedi.1921.04120040026002
Abstract

The problem presented by the various hemorrhagic conditions occurring in infancy and childhood, as well as those associated with morbid states in adults, has been extensively studied, but until recently, with confusing and inconsistent results. This is especially true of the condition known as "hemorrhagic disease of the new-born," called by many English writers "hemophilia of the new-born."

The following case report, with the results of the study of the factors of coagulation, is submitted as further evidence tending to clarify the problem of the etiology of the disease.

REPORT OF CASES 

History.  —Hospital No. 10898. Baby M, male, born Feb. 25, 1916, after a normal pregnancy and labor, entered the hospital February 28 for persistent omphalorrhagia which had had its onset early the day of entry. The family history was negative except for the presence of a + + + positive Wassermann reaction in the father's blood serum. The mother's Wassermann reaction

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