The reactions obtained with the colloidal gold test in syphilitic diseases of the central nervous system and the various forms of meningitis are fairly well established and have proved of value in diagnosis. Several investigators have reported their results with the reaction in cases of acute epidemic poliomyelitis, most of the studies having been carried out during the 1916 epidemic. These papers have been quoted at length in a previous publication1 and will not again be referred to here.
One of us (J. C. R.) previously reported1 a series of twenty-one cases including seventy-four spinal fluids examined at intervals varying from the fourth to the one hundred and twenty-third day of the disease. The results obtained in this previous series and in the present one have been fairly uniform. Any differences will be called attention to in the accompanying text.
From June to November, 1921, forty-nine cases of
REGAN JC, LITVAK A, REGAN C. THE COLLOIDAL GOLD REACTION IN ACUTE POLIOMYELITIS. Am J Dis Child. 1923;25(1):76-84. doi:10.1001/archpedi.1923.01920010081006