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September 1923

EXPERIMENTAL OBSERVATIONS ON THE ETIOLOGY OF CHOREA

Author Affiliations

ROCHESTER, MINN.
From the Division of Experimental Bacteriology, The Mayo Foundation.

Am J Dis Child. 1923;26(3):223-241. doi:10.1001/archpedi.1923.04120150030004
Abstract

Numerous investigators have made cultures of the throat, tonsils, blood and spinal fluid of patients with chorea. Collins1 isolated from the blood of a patient with severe chorea gram-positive cocci which grew in pairs, or in chains of from four to six. La Fetra2 reported the finding of Streptococcus viridans in the blood of two patients with chorea. Camisa3 isolated a diplostrptococcus from the blood of six of nine patients with chorea minor. The blood of twenty-one patients was cultured by Quigley,4 and in nine of these he found small cocci arranged in pairs and in short chains. Positive results on culturing the spinal fluid were obtained in thirteen of twenty-one cases, and the organisms in eight of the thirteen resembled those found in the blood. Poynton and Paine5 obtained a diplococcus from the spinal fluid of two patients dying with rheumatic fever associated with

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