Herpetic stomatitis and aphthous stomatitis are considered by some authors as separate diseases and by others as the earlier and later stages, respectively, of one condition. From the different modes of presentation by the various authors, one gains, in reading the textbooks in different languages, the impression that uncertainty exists as to the cause of this disorder and as to the effectiveness of any one of the numerous therapeutic measures advised. Practically all authors agree that improvement takes place, more or less spontaneously, within from one to two weeks. Individual writers, however, point out that occasionally in poorly nourished individuals serious bowel disturbances will occur during the course of the stomatitis if the utmost care is not observed in improving the condition of the mouth.
From an etiologic standpoint, toxin absorption, direct bacterial action and poor personal and general hygiene, either alone or combined. have been blamed for the development
GERSTENBERGER HJ. THE ETIOLOGY AND TREATMENT OF HERPETIC (APHTHOUS AND APHTHO-ULCERATIVE) STOMATITIS AND HERPES LABIALIS. Am J Dis Child. 1923;26(4):309-328. doi:10.1001/archpedi.1923.04120160022003