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January 1924

BILE PIGMENTS AND BILE SALTS IN THE DUODENAL JUICE OF CHILDREN

Author Affiliations

MINNEAPOLIS
From the Department of Pediatrics, University of Minnesota Medical School.

Am J Dis Child. 1924;27(1):25-27. doi:10.1001/archpedi.1924.01920070032003
Abstract

Some believe that urobilin is formed only in the intestine. Others believe that, normally, it is also formed in the liver. A reabsorption from the intestine and reexcretion through the liver are both affirmed and denied.1 It may be considered as proved that increased amounts of urobilin or urobilinogen in the stools, the urine or the duodenal juice are significant either of increased blood destruction or of hepatic disease.2

Ylppö examined the stools of fifty infants and found urobilin only after the second week of life.3 Bauman states that urobilin appears in the intestine of the new-born after the third day.4

No reports of urobilin excretion in the duodenal juice of children have hitherto been published, but one of us (R. T.) submitted the finding of urobilinogen (600 dilution units) in the duodenal juice of a child with celiac disease as evidence of hepatic involvement. This

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