In 1915, Moody and myself1 reported on the findings in the cerebrospinal fluid with the Lange colloidal gold reaction. The first of the conclusions in this paper, was: "In the cases of congenital syphilis included in this report the cerebrospinal fluid reacted to the colloidal gold chlorid solution always in the lowered dilutions, and with a marked degree of regularity strongest in the dilutions of 1:40 and 1:80." "There is a small group of cases of congenital syphilis in which the reaction is similar to that of paretic dementia."
In Table 1, I have collected a few cases of congenital syphilis, in which the reactions in general do not conform to the first statement. It will be noted in this table that Case 5 conforms very well to the second statement, and that Case 6 likewise shows a reaction similar to that obtained in paretic dementia. Both of these
GRULEE CG. SOME FURTHER OBSERVATIONS ON THE LANGE GOLD CHLORID REACTION ON THE CEREBROSPINAL FLUID IN INFANTS AND YOUNG CHILDREN. Am J Dis Child. 1924;28(2):147-151. doi:10.1001/archpedi.1924.04120200017002