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August 1924

SOME FURTHER OBSERVATIONS ON THE LANGE GOLD CHLORID REACTION ON THE CEREBROSPINAL FLUID IN INFANTS AND YOUNG CHILDREN

Am J Dis Child. 1924;28(2):147-151. doi:10.1001/archpedi.1924.04120200017002
Abstract

In 1915, Moody and myself1 reported on the findings in the cerebrospinal fluid with the Lange colloidal gold reaction. The first of the conclusions in this paper, was: "In the cases of congenital syphilis included in this report the cerebrospinal fluid reacted to the colloidal gold chlorid solution always in the lowered dilutions, and with a marked degree of regularity strongest in the dilutions of 1:40 and 1:80." "There is a small group of cases of congenital syphilis in which the reaction is similar to that of paretic dementia."

In Table 1, I have collected a few cases of congenital syphilis, in which the reactions in general do not conform to the first statement. It will be noted in this table that Case 5 conforms very well to the second statement, and that Case 6 likewise shows a reaction similar to that obtained in paretic dementia. Both of these

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