In the pediatric and general clinic of any hospital, many cases of albuminuria are discovered by the routine examination of urine in all dispensary patients. The albuminuria in these cases is due to various causes, including anemia, focal infections, orthostasis, malnutrition or faulty diets and minor respiratory infections besides the actual cases of nephritis. Many nephritis patients do not have nitrogenous retention, but it is of dietary importance to determine the presence or absence of such retention.
Complicated chemical studies are impracticable in adult dispensary work and more or less impossible in pediatric clinics. Hence the importance of the salivary urea index of Hench and Aldrich,1 a simple clinical test which, by denoting urea retention in the body and the blood, indicates the presence or absence of certain definite types of nephritis (those associated with nitrogenous retention). By the test which may be done readily in from five to
CALVIN JK, ISAACS BL. STUDIES ON THE SALIVARY UREA INDEX IN CHILDREN. Am J Dis Child. 1925;29(1):70-77. doi:10.1001/archpedi.1925.04120250073007