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Few clinicians can discuss this subject with the authority of Hutinel, who began his studies shortly after relieving Grancher in 1889, at the Clinique des Enfants-Malades. His isolated reports have finally been assembled into a volume of 232 pages, with 15 illustrations, and an earnest attempt has been made to classify these disorders, particularly in the light of recent investigations of the rôle of the ductless glands.
Hutinel cleverly contrasts the formulative or evolutionary dystrophies of early life with the regressive types seen in old age; in an early chapter, dedicated to the anomalies produced through hormonic disequilibrium, he stresses the clinical pictures in succession of thyroid, hypophyseal, suprarenal and genital deviations; in another chapter are "passed in review" the syndromes of the pluriglandular dystrophies, notably those of infantilism, obesity, "la maigreur," dwarfism, gigantism, and, unusual as it may seem to American readers, chlorosis, which Hutinel regards as something infinitely
Les Dystrophies de l'Adolescence. Am J Dis Child. 1925;29(3):432. doi:10.1001/archpedi.1925.04120270133014