As many of the reports as to results in vaccine therapy of pertussis have emanated from institutions, under which circumstance I believe the disease runs a relatively severe course, these observations were made on patients treated in private practice, in the hope that some facts as to the clinical manifestations seen might add to the accumulation of data, from which conclusions as to the best method and technic of treatment will eventually be drawn.
As objectives, the following points were designated: (1) To determine whether or not there was merit in the treatment; (2) to ascertain whether vaccine had any prophylactic value; (3) to see if such a thing as an average course for vaccine treated pertussis could be outlined; and (4) to make observations as to the optimum time of administration.
The technic employed was as follows. During a given period, every patient presenting with a definite history of
ALDRICH CA. THE CLINICAL COURSE OF VACCINE-TREATED PERTUSSIS IN PRIVATE PRACTICE. Am J Dis Child. 1925;29(4):486-491. doi:10.1001/archpedi.1925.04120280056003