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February 1926

THE CHYLOMICRON (FREE FAT) CONTENT OF THE BLOOD IN INFANTS

Author Affiliations

NEW YORK
From the Department of Pediatrics, Cornell University Medical College.

Am J Dis Child. 1926;31(2):201-217. doi:10.1001/archpedi.1926.04130020053006
Abstract

INTRODUCTION  Lipemia, or milkiness of the blood serum, has been recognized for centuries. This appearance is due to the presence of innumerable minute fatty particles which are poured into the blood from the chyle. These particles were called by Gulliver, "the molecular base of the chyle," and have had various names, such as fat dust, blood dust, hemokonia and chylomicrons. We use Gage's1 term, chylomicrons, because it has the advantage of indicating the origin and the approximate size of the particles.In spite of the importance of questions relating to the metabolism of fat, few studies are available. Until recently, such studies were hampered by the need for large quantities of blood for making chemical analyses, and by the difficulty of estimating the degree of lipemia as judged by the number of chylomicrons. Bloor,2 by means of chemical analyses, has studied the various lipoids in plasma, corpuscles and

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