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For a book to go through twelve editions may be regarded in itself as prima facie evidence of its merit. Hesitation to recommend it unreservedly to the student and to the practitioner is due to rather numerous shortcomings, some of which may be pointed out here.
Under "Arsenic" on page 14, the author states "children of the upper classes, who, like their parents, are much more sensitive to medication than are hospital patients (a physiological fact of which there is no doubt, and of very wide bearing indeed)." It is possible that such a statement is correct, but if we take into consideration the individual variations in reactions to drugs and the inability of changing such action objectively in many instances, we must object most seriously to such ex cathedra statements without references to actual data.
The observation that in some new-born infants an increase of coagulation and bleeding times
DISEASES OF CHILDREN.. Am J Dis Child. 1926;32(1):160-162. doi:10.1001/archpedi.1926.04130070169016