Through the courtesy of Leonard, we were able to obtain a supply of hexylresorcinol to try out in the treatment of chronic pyelitis in children. Our clinical material consisted largely of patients who had had urinary infections lasting for months and years, rather than for days and weeks. The group, therefore, is made up of patients very difficult to cure. In this series there were fourteen patients, four with definite anatomic lesions of the urinary tract complicating the pyelitis. The duration of the infection was less than one month in one case, between one and six months in two, one year in three, two years in two, between five and ten years in four, and between ten and fifteen years in two cases.
Bacillus coli was the infecting organism in ten cases, streptococcus in two, staphylococcus in one case, and Bacillus proteus in one.
Hexylresorcinol was administered in olive oil
HELMHOLZ HF. THE THERAPEUTIC VALUE OF HEXYLRESORCINOL IN CHRONIC PYELITIS OF CHILDHOOD. Am J Dis Child. 1926;32(3):396-400. doi:10.1001/archpedi.1926.04130090073011