A definite relationship of the various organisms found in the throat to infections of the upper respiratory tract has not been established, although the problem has been studied extensively. It is a striking observation in private practice that the clinical manifestations of infections of the upper respiratory tract at any given time tend to be similar. The prevailing infection for a time may be nasopharyngitis, frequently with complications of the ear; a little later, tonsillitis with glandular swelling is more predominant; at another time, nausea and vomiting with abdominal pain, as first described by Brennemann,1 are the clinical manifestations. For many years I have observed that in the summer, infection of the upper respiratory tract is often manifested as follicular pharyngitis, even in the presence of tonsils, which frequently spreads to the pillars, the soft palate and the mucous membrane of the cheeks.
The serious nature of the common
HELMHOLZ HF. STREPTOCOCCUS HEMOLYTICUS IN THE NASOPHARYNX OF CHILDREN. Am J Dis Child. 1931;42(2):328-334. doi:10.1001/archpedi.1931.01940140068005