Pathologic conditions of the gallbladder are admittedly of rare occurrence in infancy and childhood. Textbooks dismiss the subject of disturbances of the gallbladder with a few lines. Thus, Porter1 stated that "pathological involvement of the gallbladder during childhood is practically unknown," and Griffith and Mitchell2 mentioned "cholelithiasis of a chronic nature as an occasional complication of typhoid fever." A search of the literature reveals that about 150 cases of all types of diseases of the gallbladder in children have been collected to the present time. In 1923, Kellogg3 tabulated 64 cases, and Beals4 collected 60 additional cases. Reed and Montgomery5 reported a series of 18 cases of acute cholecystitis in children up to the age of 10 years, occurring during or immediately after an attack of typhoid fever. In 10 per cent of these cases the patients were operated on and the gallbladders were removed.
MOHR M. ACUTE CHOLECYSTITIS IN CHILDHOOD. Am J Dis Child. 1931;42(2):372-375. doi:10.1001/archpedi.1931.01940140112010