The excuse for reporting a single case lies, in this instance, in the twofold fact that it is unique in our experience, and that we have been able to find but one other apparently identical case in the literature.
For about eight years, or since he was 10 months old, a boy with a striking general deformity of the body has been in and out of our clinic at the Children's Memorial Hospital. From the start an object of curiosity, he became increasingly so as he grew older and the deformities became more evident (fig. 1). The early diagnosis of rickets—made even then with much reservation—was soon abandoned. His diet and hygiene and his general care by an intelligent mother had all been unexceptionable. Beyond the period of infancy the whole clinical picture was unlike anything that could be attributed to rickets. Free consultation together with sporadic attempts at a
MEYER HF, BRENNEMANN J. A RARE OSSEOUS DYSTROPHY (MORQUIO). Am J Dis Child. 1932;43(1):123–135. doi:10.1001/archpedi.1932.01950010130012