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Reports of total unilateral hypertrophy or hemihypertrophy are comparatively rare in medical literature. The earliest case was reported by Wagner, in Germany, in 1839; in 1879, Osler gave the number of reported cases of congenital hemihypertrophy as twelve. Gesell, in 1921, made a careful search of the literature and collected forty cases, which included one of his own. In 1927, he was able to add thirteen to this number, making a total of fifty-three cases. Wiseberg and Halperin each reported a case in 1931. The present case is reported for two reasons: (1) because it presents an unusual anatomic anomaly, congenital in origin and (2) because the comparative rarity of the condition makes it seem worth while to add another case to the few recorded.
REPORT OF A CASE
The patient was a white girl, 3½ years of age, who first came to the pediatric clinic of the outpatient department
GLANZER J. TOTAL UNILATERAL HYPERTROPHY. Am J Dis Child. 1933;45(5):1056-1063. doi:10.1001/archpedi.1933.01950180128012