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The author found in the last ten years a greater number of people in England than on the continent suffering from a peculiar symptom complex embracing three main groups of symptoms: gastro-intestinal, cutaneous and general. He found a number of people with constipation, dryness in the mouth and throat, impaired appetite, nausea and, later, vomiting of every kind of food soon after it was taken. Roentgen examination revealed only colonic stasis. Certain conditions of the skin also appear with greater frequency; acute and chronic urticaria, infantile eczema, herpes and persistent furunculosis. The finger-nails become soft and brittle, lose their luster and appear opaque and thickened. The third group of symptom complexes is evidenced by frequent attacks of neuralgia and twitching of the legs, pain in the fingers and toes, arthralgia of a severe type, giddiness, excessive perspiration and anemia. Nervous symptoms comprise depression and even melancholia, loss of energy and
The Clinical Aspect of Chronic Poisoning by Aluminum and Its Alloys.. Am J Dis Child. 1933;46(3):698. doi:10.1001/archpedi.1933.01960030227018