[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 50.16.107.222. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Other Articles
October 1933

EFFECT OF LACTOSE ON RICKETS IN RATS

Author Affiliations

LAFAYETTE, IND.
From the Home Economics Department, Louisiana Agricultural Experiment Station.

Am J Dis Child. 1933;46(4):786-793. doi:10.1001/archpedi.1933.01960040084007
Abstract

Lactose has been shown to increase the acidity of the intestinal tract. Rickets seems to be associated with an alkaline reaction in the intestinal tract. Coupling these facts led to this investigation to determine the effect of lactose on rickets.

A connection between increased alkalinity of the intestinal tract and rickets has been pointed out by several investigators.

Zucker and Matzner1 noted a lowering of the fecal ph of rachitic rats when antirachitic substances were added to the diet.

Abrahamson and Miller2 suggested that the lowering of the acidity of the intestinal tract on a rachitic diet, with the resulting formation of insoluble calcium phosphate, might be an important factor in the deficiency of calcium absorption and deposition on rachitic diets.

Grayzel and Miller3 found that the entire intestinal tract of dogs showed acidity on all the diets used except the rickets-producing diet, which caused a rise

First Page Preview View Large
First page PDF preview
First page PDF preview
×