Hypereosinophilia is found in many diseases. Kilduffe1 lists the conditions as follows: myelogenous leukemia, bronchial asthma, scarlatina, various skin diseases, helminthic infestations, gonorrhea, active tuberculosis and convalescence from pyogenic infections. The occurrence of well marked eosinophilia in cases of carcinoma of the stomach,2 breast3 and other organs has been reported. In the cases of carcinoma the percentage of eosinophils ranged from 5 to 48.
Persistent and unexplained eosinophilia has been described by several authors. The term "familial" or "constitutional" is used to indicate eosinophilia of unexplained origin in several members of a family. In 1911 Klinkert4 reported a family of six with eosinophil counts varying from 7 to 15 per cent. Gaugain5 reported a mother and three children with counts of 9, 10, 14 and 15 per cent. Armand-Delille, Hurst and Sorapure6 reported a family in which a boy of 8 years had an
KELLY GF. EOSINOPHILIA. Am J Dis Child. 1935;49(2):403–407. doi:10.1001/archpedi.1935.01970020118011