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A painting of extraordinary pediatric interest hangs in the Boston Museum of Fine Arts, a Madonna and Child by Andrea Mantegna (1431-1506), who helped link the mystical middle ages with the mate
Cretin, mongol or a combination of the two. (Courtesy of Dr. Harold L. Higgins of Boston.) rialism which was to follow. Mantegna, favorite pupil of Squarcione, who adopted him and made him his heir, created a new style, and credit is due him for some of the most beautiful paintings in existence.
The child in the picture presents a diagnostic puzzle, for he shows some features of a cretin and some of a mongol and perhaps a mixture of the two, a clinical picture occasionally seen. Against the diagnosis of cretinism is the lack of tissue changes about the eyes, but the hair is coarse, the tongue is prominent, the mucous membranes are thick and the hands are
RUHRAH J. CRETIN OR MONGOL, OR BOTH TOGETHER. Am J Dis Child. 1935;49(2):477-478. doi:10.1001/archpedi.1935.01970020192019