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June 1935

PATHOLOGIC CHANGES IN ASTHMATIC INFANTS

Am J Dis Child. 1935;49(6):1531-1539. doi:10.1001/archpedi.1935.01970060135011
Abstract

It is noteworthy that among the cases of asthma in which autopsy was performed that are recorded in the literature, there are very few in children and none in infants. In 1931 Walzer1 recorded in his summary of the literature on 33 deaths from asthma the cases of 2 children, aged 2 years and 15 months, respectively, in whom asthma had been present for fifteen and for five months, respectively. In the case of five months' duration (Huber and Koessler) the diagnosis of "bronchial asthma" was questioned because of the presence of a large thymus and other characteristics of status thymicolymphaticus.

Since then, MacDonald2 has added the case of a 13 year old girl to about 15 additional records of deaths from asthma reported in the literature. The question arises as to whether or not asthmatic patients die of this disease during the early years of life or

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