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November 1935

THE ICTERUS INDEX IN THE NEW-BORN INFANT

Author Affiliations

SALT LAKE CITY
From the Newborn Department of the Holy Cross Hospital.

Am J Dis Child. 1935;50(5):1143-1151. doi:10.1001/archpedi.1935.01970110051007
Abstract

Development of relatively accurate methods for the quantitative determination of the bilirubin content of the blood serum has led to acceptance of an icterus index of from 4 to 6 as normal for the adult. Latent jaundice is said to be present up to an index of 15, at which point clinical manifestations of jaundice appear. The need for several cubic centimeters of blood to perform these tests necessitates venipuncture, a requirement acting somewhat as a deterrent in determining the icterus index in infants and probably accounting for the dearth of routine studies of the bilirubin content of the neonatal blood serum. The method devised by Davis1 for the use of small amounts of blood, if practical, would offer a simple way of doing this. Briefly, it consists of drawing into a capillary tube a few drops of blood obtained by puncture of the skin. The serum is separated

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