Acute myelogenous leukemia occurring prior to the age of 4 years is unusual. Noma, once quite common, is now a clinical curiosity. Generalized acute streptococcic dermatitis, formerly known as "hospital pemphigus," occurs infrequently. To find all three of these unusual but interesting conditions combined in one case seems to justify a report.
REPORT OF A CASE
History.—A Negro boy 3 years of age was admitted to the University Hospital because of "sore mouth."When 9 weeks of age the child was brought to the university dispensary because of persistent coryza. Conservative treatment soon restored him to health. Periodic examinations indicated that he had had a normal development.Three weeks before his admission to the hospital the child's mother noticed that both his ankles were swollen and edematous and that he walked with a peculiar limping gait. Examination revealed large, inflamed tonsils, diffuse bilateral cervical adenopathy and an inflammatory periarticular
HICKEN NF, ELDREDGE RB. ACUTE MYELOGENOUS LEUKEMIA COMPLICATED BY NOMA AND ACUTE STREPTOCOCCIC DERMATITIS. Am J Dis Child. 1935;50(6):1455–1464. doi:10.1001/archpedi.1935.01970120107009