The so-called Danlos or Ehlers-Danlos syndrome consists of three symptoms: (1) pronounced fragility of the skin and its blood vessels, with breaking, splitting and the formation of hematomas and pseudotumors subsequent to the slightest trauma (dermatorrhexis-fragilitas cutis), (2) a more or less pronounced hyperlaxity and hyperelasticity of the skin (dermatochalasis-laxitas cutis) and (3) more or less pronounced hyperlaxity or hyperflexibility of the joints (arthrochalasis-laxitas articularis).
I have had the opportunity of observing three patients with this syndrome, and I wish to report their cases, not to add much to the descriptions of this subject which have appeared in the European literature and in the paper by Tobias1 in this country but because it seems to me that little attention has been paid here to this syndrome by dermatologists, pediatricians and orthopedic surgeons. Furthermore, I think that the terminology needs revision, so that the importance of one of the symptoms
RONCHESE F. DERMATORRHEXISWITH DERMATOCHALASIS AND ARTHROCHALASIS (THE SO-CALLED EHLERS-DANLOS SYNDROME). Am J Dis Child. 1936;51(6):1403–1414. doi:10.1001/archpedi.1936.01970180149012