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It is refreshing to find investigators who are content to study and report the leukocytic changes in so common a disorder as grip without claiming any great significance for their work. These authors present their results in graphs representing the total number of leukocytes of each type per cubic millimeter. They are of the opinion that such a presentation gives a clearer picture of the actual response of the hematopoietic system than the usual figures, the total number of leukocytes with differential percentages. It is interesting to note that the actual increase in polymorphonuclear cells with a shift to the left, which has recently been pointed out by some investigators as indicating the presence of acute appendicitis, was noted in a large number of the authors' cases. This study should be of value in showing the variation in what might be considered the normal response to mild infection.
Die Haematologie der banalen, grippalen Infecte bei Säuglingen und Kleinkindern.. Am J Dis Child. 1936;52(1):251. doi:10.1001/archpedi.1936.04140010260025