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Case Reports
September 1936

CONGENITAL APLASIA OF THE ISLANDS OF LANGERHANS WITH DIABETES MELLITUS

Author Affiliations

NEW YORK
From the Department of Pathology of the New York Hospital, New York, and the Cornell University Medical College, Ithaca, N. Y.

Am J Dis Child. 1936;52(3):627-632. doi:10.1001/archpedi.1936.04140030117010
Abstract

Diabetes mellitus in infants and children presents problems which do not exist in a study of the disease in adults. Warren1 stated that the most characteristic pathologic change of the islands of Langerhans in diabetic children is lymphocytic infiltration. In a few cases the number and amount of island tissues are decreased. In a rare case there is apparently absence of cells which may be recognized morphologically as mature islands of Langerhans. The present report presents a case of the latter type.

REPORT OF A CASE  S. T., a 13 year old white girl born in America of Italian parents, was admitted to the New York Hospital because of pain in the side, which had been present for twenty-four hours. (Dr. Eugene DuBois supplied the clinical data.)Family History.—The father and mother were Italian-born and 44 and 35 years of age, respectively. The mother had had 6 pregnancies,

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