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Case Reports
October 1937

HYPERTROPHIC PULMONARY OSTEO-ARTHROPATHY IN INFANTS AND IN CHILDREN

Author Affiliations

ROCHESTER, MINN.
From the Section on Pediatrics, the Mayo Clinic.

Am J Dis Child. 1937;54(4):795-805. doi:10.1001/archpedi.1937.01980040099008
Abstract

In pediatric literature little emphasis has been placed on the fact that clubbed fingers and toes may be but one manifestation of the condition which has been designated as hypertrophic pulmonary osteoarthropathy, or Marie-Bamberger's1 disease. The reason for this lack of emphasis is obvious. Clubbed fingers are found in young patients with relative frequency, but concomitant changes in other parts of the skeleton are infrequently found.

That the condition does occasionally occur in a young person is attested by the reports of Bamberger,1b Whitman,2 Taylor,3 Gilbert and Fournier,4 Gillett (quoted by Miller5), Davis,6 Hyman and Herrick,7 Bryan8 and Schippers.9 As Locke10 emphasized, the changes in the digits and the Skeleton are nearly always secondary to some primary disease of the lungs, heart, liver or other organ or part of the body, suppurative pulmonary disease being responsible for the changes

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