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Professor Klare points out the frequency with which various symptoms of nonspecific origin displayed by tuberculin-sensitive children of hyperreactive so-called exudative-lymphatic constitution lead to erroneous diagnoses of clinically active tuberculosis. He stresses the necessity of exercising judgment, based not only on information yielded by special laboratory and clinical studies but also on a comprehensive knowledge of inherent familial and individual traits, in correctly differentiating infected children who do from those who do not require institutional care. His vigorous remonstrance against the frequent failure of physicians to exercise discrimination in recommending the institutionalization of infected children unquestionably is sound.
In addition to the confusion in diagnosis occasioned by the exaggeration of clinical manifestations of specific and nonspecific infections characteristic of the exudative-lymphatic type of constitution, the tendency to hyperreaction has a prognostic significance, according to the author, in that the hypersensitivity exerts a favorable influence on the course of tuberculosis. Apparently,
Anleitung zur Konstitutionsdiagnostik bei kindlicher Tuberkulose (an Hand von praktischen Beispielen).. Am J Dis Child. 1937;54(4):964. doi:10.1001/archpedi.1937.01980040268018