The pathologic and clinical concepts of malignant tumors of blood vessels have been the subjects of much discussion in recent years. The differences of opinion among numerous observers are evidenced by the fact that the condition at various times has been called angioma hypertrophicum, hemangio-endothelioma, angioblastoma, hemangio-endothelioblastoma, endotheliosarcoma, endothelioblastoma and endothelioma.
Aside from the publications of Taylor and Moore,1 Jaffé,2 Geschickter and Keasbey3 and others,4 cases of multiple endotheliomas or hemangio-endotheliomas with cutaneous involvement have not occupied much space in the literature. Jaffé,2 in a classic review of the literature in 1929, collected about 20 cases, the majority having occurred in adults. The rarity of the condition in children, the peculiarities of the clinical course in the present case and its fatal termination warrant the presentation of this case.
REPORT OF A CASE
S. C., a 6 week old boy of Italian parentage, was first
DORDICK JR. MULTIPLE MALIGNANT HEMANGIO-ENDOTHELIOMAS IN AN INFANT. Am J Dis Child. 1938;55(3):559-565. doi:10.1001/archpedi.1938.01980090107012