Several years ago, Exton and Rose1 published their results with the use of a one hour, two dose alimentary dextrose tolerance test for adult subjects; they claimed for it, in addition to the important factor of time saving, greater specificity and reliability than are found in the older tests. Kelly, Beardwood and Fowler2 confirmed the usefulness of this new procedure. Gould, Altshuler and Mellen,3 in comparative studies, likewise corroborated the advantages of this shorter test, finding, however, a necessity for modification of both the technic and the diagnostic criteria. It seems apparent that if applicable with equal success to infants and children, such a test would be especially advantageous for them and should find ready advocation for its use.
This newer test is based on the paradoxic law, long ago expressed by Allen,4 that "... whereas in normal individuals the more sugar given the more is utilized,
COOPERSTOCK M, GALLOWAY JM. ONE HOUR, TWO DOSE DEXTROSE TOLERANCE TEST. Am J Dis Child. 1938;55(6):1221-1232. doi:10.1001/archpedi.1938.01980120083007