Ossification in the wrist and forearm has been widely used by anatomists, educators and other investigators as an index of anatomic age. As such, it has been correlated with mental age, the intelligence quotient and other factors, and important conclusions have been drawn from the findings. Only rarely has the suggestion been made that this index might be modified by the state of nutrition, although it seems almost self evident that any prolonged deficiency or marked improvement in the diet would have an appreciable effect on development of bone.
The present study was prompted by the desire to study this question under experimental conditions. An excellent opportunity was presented to do this in connection with a larger study, which was being carried out in a children's institution.1 The purpose of the project was to determine whether an increase in the amount of milk consumed to make a total of
MacNAIR V, ROBERTS LJ. EFFECT OF A MILK SUPPLEMENT ON THE PHYSICAL STATUS OF INSTITUTIONAL CHILDRENII. OSSIFICATION OF THE BONES OF THE WRIST. Am J Dis Child. 1938;56(3):494–509. doi:10.1001/archpedi.1938.01980150014002