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November 1938


Author Affiliations

From the Department of Medicine and the Department of Chemistry, Northwestern University Medical School.

Am J Dis Child. 1938;56(5):975-984. doi:10.1001/archpedi.1938.01980170021004

Little information is available concerning the effect of iron deficiency during pregnancy on the iron content and blood hemoglobin content of the young. Fetzer,1 in 1913, determined the iron content of rabbits born to females receiving high and low iron diets. His results, although not entirely conclusive, showed a correlation between the female's intake of iron and the iron content of the young. In rats it has been repeatedly demonstrated that animals of the second generation fed a diet deficient in iron show anemia during the early weeks of life.2 A few determinations of the hemoglobin level at birth have revealed normal values. Similar observations have been reported for mice3 and for pigs.4 These studies do not present conclusive evidence in favor of congenital deficiency of iron, because the young received iron-deficient diets during a period of active growth. Parsons and others5 have recently reported

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