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This monograph advances the novel concept that the prognosis of open tuberculosis depends on the constitutional type of the individual patient. The term "constitutional type" is defined by the authors as an inherited, unalterable state of reactivity to exogenous and endogenous stimuli. After reviewing and analyzing the case material in their institution from 1916 to 1936, they conclude that the child with open tuberculosis who is of the exudative-lymphatic constitutional type has the best prognosis. The following criteria were employed in placing a child in this category:
A history of frequent illnesses of inflammatory nature, especially a tendency to infections of the throat
Light hair and light eyes
A hyperactive skin, as evidenced by dermographism and a marked tuberculin reaction
Enlarged cervical lymph nodes
In the monograph entitled "Anaemia of Infancy and Early Childhood" (Medicine 15:307 [Sept.] 1936) Hugh W. Josephs, discussing
Die offene Lungentuberkulose bei Kindern und Jugendlichen.. Am J Dis Child. 1938;56(5):1180. doi:10.1001/archpedi.1938.01980170226025