During the past decade there has been a tremendous spurt in interest, reflected by increasing numbers of reports in the literature, concerning universal edema of the newborn, icterus gravis and anemia of the newborn. With this increased interest the concept has emerged that these three different clinical pictures are actually manifestations of the same disease process.
The cases which we are presenting in this report we believe to be of great significance. In regard to severity they represent the opposite extremes of the related group included in so-called erythroblastosis fetalis. These widely divergent clinical pictures occurred in identical twins after the mother had given birth to seven normal children. At the time of writing, both children are over 1 year of age, a situation unique in the literature on this subject, for it has been universally stated that infants with congenital hydrops who are not born dead always perish shortly
SHAPIRO LM, COHEN P. ANEMIA OF NEWBORN IN ONE IDENTICAL TWIN AND UNIVERSAL EDEMA OF NEWBORN IN THE OTHERWITH SURVIVAL IN BOTH CASES. Am J Dis Child. 1939;58(5):1050-1066. doi:10.1001/archpedi.1939.01990100132013