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February 1940


Author Affiliations

From the Department of Pediatrics, Yale University School of Medicine, and the Pediatric Service of the New Haven Hospital and Dispensary.

Am J Dis Child. 1940;59(2):281-286. doi:10.1001/archpedi.1940.01990130064004

Lancefield1 has demonstrated that hemolytic streptococci can be divided into distinct groups by means of a precipitin test which identifies specific carbohydrates. Strains from human disease were observed to fall into one group, which she designated as group A.2 Her groups B, C, D, E, F and G consisted of animal strains and human saprophytes.3

With the wider employment of the Lancefield group precipitin test, some exceptions have appeared. Hemolytic streptococci of groups other than A have been found in association with infection, even fatal infection, in man. Hare4 and Fry5 isolated group B hemolytic streptococci from a total of 11 patients with puerperal sepsis; in 4 of the 5 patients who died of the infection the organisms were recovered from the blood. Hare4 found that Griffith's6 type 7 hemolytic streptococcus, recovered from human erysipelas, fell into Lancefield's group C. Plummer7 classified

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