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February 1940

HUMAN HEMOLYTIC STREPTOCOCCI FROM DISEASES OF CHILDREN

Author Affiliations

NEW HAVEN, CONN.
From the Department of Pediatrics, Yale University School of Medicine, and the Pediatric Service of the New Haven Hospital and Dispensary.

Am J Dis Child. 1940;59(2):281-286. doi:10.1001/archpedi.1940.01990130064004
Abstract

Lancefield1 has demonstrated that hemolytic streptococci can be divided into distinct groups by means of a precipitin test which identifies specific carbohydrates. Strains from human disease were observed to fall into one group, which she designated as group A.2 Her groups B, C, D, E, F and G consisted of animal strains and human saprophytes.3

With the wider employment of the Lancefield group precipitin test, some exceptions have appeared. Hemolytic streptococci of groups other than A have been found in association with infection, even fatal infection, in man. Hare4 and Fry5 isolated group B hemolytic streptococci from a total of 11 patients with puerperal sepsis; in 4 of the 5 patients who died of the infection the organisms were recovered from the blood. Hare4 found that Griffith's6 type 7 hemolytic streptococcus, recovered from human erysipelas, fell into Lancefield's group C. Plummer7 classified

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