During the summer and fall of 1938, 10 children were admitted to the St. Louis Children's Hospital with symptoms suggestive of some type of encephalitis. The clinical picture presented by these children was not uniform, but in each case there was evidence of cerebral involvement. In several instances (cases 1 to 6 in the accompanying table) the condition closely resembled St. Louis encephalitis manifested by children in 1933 and 1937. In 1 case (7) the clinical symptoms, although less definite, still simulated the milder form of this disease seen during the outbreak of 1937. The condition in another case (8) was suggestive of neuronitis. In case 9 the illness, which left striking residuals, was comparable to type A rather than to type B encephalitis, and in case 10 a tentative diagnosis of atypical polioencephalomyelitis was made.
Two other children (cases 11 and 12) observed during this period presented postencephalitic residuals.
SMITH MG, LENNETTE EH, BLATTNER RJ. ETIOLOGIC STUDIES OF SPORADIC CASES OF ENCEPHALITIS OCCURRING IN THE ST. LOUIS AREA IN 1938. Am J Dis Child. 1940;59(3):509-514. doi:10.1001/archpedi.1940.01990140052007