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September 1940

ESTIMATION OF VITAMIN D IN BLOOD SERUMII. LEVEL OF VITAMIN D IN HUMAN BLOOD SERUMS

Author Affiliations

CINCINNATI
From the Children's Hospital Research Foundation and the Department of Pediatrics, University of Cincinnati.

Am J Dis Child. 1940;60(3):606-614. doi:10.1001/archpedi.1940.02000030138012
Abstract

In a previous communication a method for the estimation of vitamin D in blood serum was described.1 It was shown that the level of vitamin D in the serum of animals can be raised by a single administration of a large dose of viosterol and that the surplus of vitamin D disappears from the serum within a few weeks. In addition, the results of a number of estimations in serums of children and adults were reported.

In the present study we wish to supplement the data concerning the level of vitamin D in human serums. It seems desirable to know not only the average value of the vitamin D in human serums but the variations which may be expected. Since those variations, which may be due to physiologic fluctuations or to the limitations of the method, are rather large, a knowledge of the fluctuations observed in the blood of

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