In this paper we are presenting a study of 70 patients with sepsis associated with infections of the upper respiratory tract: cervical adenitis, sinus thrombosis and inflammation of the accessory nasal sinuses. All of them had acute pharyngitis; a small number had pharyngitis as the sole complication. We studied the effect these foci exercised on the course of the sepsis. We also considered the effect of sepsis on these complications of acute pharyngitis. The 70 patients were part of a series of 320 children with sepsis of all types.
Blood culture studies were made for all patients with fever admitted to the pediatric wards between 1931 and 1935. The blood cultures were made according to standard methods by an intern assigned to the service. All the work was supervised by one person, insuring a good degree of uniformity in results throughout the years during which these cultures were made.
KANOF A, KRAMER B. RELATION OF SEPSIS TO INFECTIONS OF THE UPPER RESPIRATORY TRACT. Am J Dis Child. 1940;60(5):1067-1081. doi:10.1001/archpedi.1940.02000050051006