Several cases of intestinal obstruction in the newborn due to meconium have been reported. Some have termed the condition "meconium ileus," a name which seems particularly appropriate, as undoubtedly ileus is present at some time in every case and the cause is inspissated meconium.
In these cases the bowel is blocked by thick gummy meconium, and rupture may follow the first feeding. Boyd1 stated that in a number of cases there has been a congenital stenosis of the opening of the pancreatic duct with dilatation of the duct system and fibrosis of the tissue (Kornblith and Otani2) and also that Farber reported in a personal communication that he had observed this pancreatic lesion in twins, both of whom died. Bullowa and Brennen,3 in 1919, were the first to describe this condition in the newborn. The subject was well summarized by Dodd4 in 1936. Recently Anderson and
BRONAUGH W, LATTIMER RD. INTESTINAL OBSTRUCTION FROM INSPISSATED MECONIUM. Am J Dis Child. 1940;60(6):1371-1374. doi:10.1001/archpedi.1940.02000060129012