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May 1941


Author Affiliations

From the Sloane Hospital for Women, the Babies Hospital and the Departments of Obstetrics and Gynecology and of Pediatrics of Columbia University College of Physicians and Surgeons.

Am J Dis Child. 1941;61(5):958-980. doi:10.1001/archpedi.1941.02000110046005

Physiologic hyperbilirubinemia during the early postnatal period has been observed by many investigators. The stimulus and justification for still another study of the phenomenon have come from improvements in methods. A simple photoelectric technic for the analysis of small samples has made it possible for the first time to record the changes in the level of bilirubin in the serum by means of daily observations on a large number of infants. In the present study such measurements were started on the first day of life after the level of bilirubin in serum from the umbilical cord had been determined. At the time of each analysis the presence or absence of clinical icterus in the infant was recorded. The data have been examined for interrelations among such factors as the concentration of bilirubin in the cord serum, the maximum intensity of the process, the age at the time the maximum level

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