In this article are reported observations on the course and prognosis in 188 cases of hemorrhagic nephritis in persons below the age of 15 years who were observed at the Strong Memorial and Rochester Municipal Hospitals between June 1926 and October 1939. Since one of these hospitals has facilities for the care of contagious diseases, the cases of nephritis developing as complications of such diseases are included in this study.
The diagnosis of nephritis in these cases was based on the occurrence of albumin, blood and casts in the urine, with variable degrees of edema, hypertension, anemia and nitrogen retention. There was nearly always a history of a recent preceding infection, usually of the respiratory tract. Only 3 cases are included in which the diagnosis was based on what might be called "minimal evidence." In all 3 there were albuminuria after an acute infection and on two or more occasions
GACHET FS. COURSE AND PROGNOSIS OF HEMORRHAGIC NEPHRITIS IN CHILDREN. Am J Dis Child. 1941;61(6):1175–1192. doi:10.1001/archpedi.1941.02000120047003