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March 1942

WHOOPING COUGH VACCINE

Author Affiliations

ATLANTA, GA.

Am J Dis Child. 1942;63(3):453-466. doi:10.1001/archpedi.1942.02010030023002
Abstract

This report is a continuation of the work published in September 19361 and describes a comprehensive study of seven different vaccines.

  1. SAUER'S REGULAR VACCINE (10 BILLION COUNT) The study of this vaccine was covered in the previous paper.

  2. COMBINED DIPHTHERIA TOXOID AND PERTUSSIS VACCINE B-5325

This vaccine contained 20 billion pertussis organisms per cubic centimeter and 20 Lf units of diphtheria toxoid.

The vaccine was given in three doses at weekly intervals: 1 cc., 2 cc. and 2 cc. The local reactions were slightly greater than those produced by the regular 20 billion count vaccine. The systemic reactions were the same as with the 20 billion count vaccine.

All patients were given Schick tests one week before receiving the vaccine, and all those given this vaccine had positive reactions. Three months after the last injection of vaccine they were again given Schick tests, and at this time the reactions were

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