One of the distinctive features of juvenile diabetes is its occurrence in a period of life in which the person lives under the conditions of growth and development. Thus it is evident that there are three possibilities: (1) Growth and development may influence the course of diabetes, (2) diabetes may influence the growth and development of the child or (3) there may be no interrelationship.
That deviations from normal trends occur in diabetes was shown as early as 1925. Joslin, Root and White,1 reporting on the growth and development of juvenile diabetic patients, observed that a group of long duration preinsulin survivors exhibited retardation of growth, yet the average height of the entire series exceeded the Baldwin and Wood standard average for their age. It was suggested at this time that the potential diabetic child was tall and that in certain cases of long duration stunting resulted. In the
WAGNER R, WHITE P, BOGAN IK. DIABETIC DWARFISM. Am J Dis Child. 1942;63(4):667-727. doi:10.1001/archpedi.1942.02010040035003