December 1942


Author Affiliations

Director of the branch laboratory, Ontario Department of Health, Fort William, Ontario, Canada.

Am J Dis Child. 1942;64(6):1097. doi:10.1001/archpedi.1942.02010120137011

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To the Editor:—On pages 485 and 486 of the September 1942 issue of the American Journal of Diseases of Children, under the heading "Case Reports," there is an article by Koch and Kaplan entitled "Castor Bean Poisoning." In the last paragraph the authors state that there is no specific antidote for this condition. They further state that the mortality in a series of 150 cases was 6 per cent.

As it is perfectly feasible to make an antiserum against the toxin, ricin, by inoculating rabbits with increasing doses of ricin, should not steps be taken by some society to induce one of the companies manufacturing biologicals to prepare this specific antiserum and have the fact that this exists publicized, so that it may be used in future cases of castor bean poisoning? It would seem logical that the mortality rate could thus be reduced to a minimum. I suppose

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